Survivin Blockade Sensitizes Rhabdomyosarcoma Cells for Lysis by Fetal Acetylcholine Receptor–Redirected T Cells

Cellular immunotherapy may provide a strategy to overcome the poor prognosis of metastatic and recurrent rhabdomyosarcoma (RMS) under the current regimen of polychemotherapy. Because little is known about resistance mechanisms of RMS to cytotoxic T cells, we investigated RMS cell lines and biopsy sp...

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Vydáno v:Am J Pathol
Hlavní autoři: Simon-Keller, Katja, Paschen, Annette, Hombach, Andreas A., Ströbel, Philipp, Coindre, Jean-Michel, Eichmüller, Stefan B., Vincent, Angela, Gattenlöhner, Stefan, Hoppe, Florian, Leuschner, Ivo, Stegmaier, Sabine, Koscielniak, Ewa, Leverkus, Martin, Altieri, Dario C., Abken, Hinrich, Marx, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746952/
https://ncbi.nlm.nih.gov/pubmed/23562272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.02.017
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