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Inactivation of Glyceraldehyde-3-phosphate Dehydrogenase by the Dopamine Metabolite, 3,4-Dihydroxyphenylacetaldehyde
BACKGROUND: The aldehyde metabolite of dopamine, 3,4-dihydroxyphenylacetaldehyde (DOPAL) is an endogenous neurotoxin implicated in Parkinson’s Disease. Elucidating protein targets of DOPAL is essential in understanding it’s pathology. The enzyme, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a...
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| Publicat a: | Biochem Biophys Res Commun |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5746426/ https://ncbi.nlm.nih.gov/pubmed/28830811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.08.067 |
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