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Regulation of PD-1/PD-L1 pathway and resistance to PD-1/PD-L1 blockade

Immune checkpoint blockades, such as inhibitors against programmed death 1 (PD-1) and its ligand (PD-L1), have received extensive attention in the past decade because of their dramatic clinical outcomes in advanced malignancies. However, both primary and acquired resistance becomes one of the major...

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發表在:Oncotarget
Main Authors: Bai, Jie, Gao, Zhitao, Li, Xiang, Dong, Liang, Han, Weidong, Nie, Jing
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746415/
https://ncbi.nlm.nih.gov/pubmed/29299180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22690
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