Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS

Chimeric Antigen Receptor (CAR) T-cells have emerged as a powerful immunotherapy for various forms of cancer and show promise in treating HIV-1 infection. However, significant limitations are persistence and whether peripheral T cell-based products can respond to malignant or infected cells that may...

詳細記述

保存先:
書誌詳細
出版年:PLoS Pathog
主要な著者: Zhen, Anjie, Peterson, Christopher W., Carrillo, Mayra A., Reddy, Sowmya Somashekar, Youn, Cindy S., Lam, Brianna B., Chang, Nelson Y., Martin, Heather A., Rick, Jonathan W., Kim, Jennifer, Neel, Nick C., Rezek, Valerie K., Kamata, Masakazu, Chen, Irvin S. Y., Zack, Jerome A., Kiem, Hans-Peter, Kitchen, Scott G.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746250/
https://ncbi.nlm.nih.gov/pubmed/29284044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006753
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