Stem-cell Based Engineered Immunity Against HIV Infection in the Humanized Mouse Model

With the rapid development of stem cell-based gene therapies against HIV, there is pressing requirement for an animal model to study the hematopoietic differentiation and immune function of the genetically modified cells. The humanized Bone-marrow/Liver/Thymus (BLT) mouse model allows for full recon...

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Bibliographische Detailangaben
Veröffentlicht in:J Vis Exp
Hauptverfasser: Zhen, Anjie, Rezek, Valerie, Youn, Cindy, Rick, Jonathan, Lam, Brianna, Chang, Nelson, Zack, Jerome, Kamata, Masakazu, Kitchen, Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: MyJove Corporation 2016
Schlagworte:
Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993349/
https://ncbi.nlm.nih.gov/pubmed/27404517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54048
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