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The implication from RAS/RAF/ERK signaling pathway increased activation in epirubicin treated triple negative breast cancer

BACKGROUND: Triple negative breast cancer (TNBC) is not sensitive to RAS/RAF/ERK signaling pathway (ERK pathway) targeting therapy, due to the absence of excessive activation of ERK pathway. However, the kinase cascades might be activated after chemotherapy in TNBC. Here we aimed to predict whether...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huang, Jianbo, Luo, Qingqing, Xiao, Yun, Li, Hongyuan, Kong, Lingquan, Ren, Guosheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746140/
https://ncbi.nlm.nih.gov/pubmed/29296238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22604
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