Insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs

BACKGROUND: Acute infection promotes skeletal muscle wasting and insulin resistance, but the effect of insulin on energy and substrate sensing in skeletal muscle of chronically infected neonates has not been studied. METHODS: Eighteen 2-d-old pigs underwent cecal ligation and puncture (CLP) or sham...

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Pubblicato in:Pediatr Res
Autori principali: Manjarín, Rodrigo, Suryawan, Agus, Koo, Sue J., Wilson, Fiona A., Nguyen, Hanh V., Davis, Teresa A., Orellana, Renán A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746053/
https://ncbi.nlm.nih.gov/pubmed/27508897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.129
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