PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT

BACKGROUND: Golgi Membrane Protein 1 (GOLM1), a protein involved in the trafficking of proteins through the Golgi apparatus, has been shown to be oncogenic in a variety of human cancers. Here, we examined the role of GOLM1 in the development of human glioma. METHODS: qRT-PCR, immunohistochemistry, a...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Xu, Ran, Ji, Jianxiong, Zhang, Xin, Han, Mingzhi, Zhang, Chao, Xu, Yangyang, Wei, Yuzhen, Wang, Shuai, Huang, Bin, Chen, Anjing, Zhang, Di, Zhang, Qing, Li, Wenjie, Jiang, Zheng, Wang, Jian, Li, Xingang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745991/
https://ncbi.nlm.nih.gov/pubmed/29282077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0665-3
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