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Impact of FHIT loss on the translation of cancer-associated mRNAs
BACKGROUND: FHIT is a genome caretaker/tumor suppressor that is silenced in >50% of cancers. Although it was identified more than 20 years ago, questions remain as to how FHIT loss contributes to cancer, and conversely, how FHIT acts to maintain genome integrity and suppress malignancy. Fhit belo...
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| Udgivet i: | Mol Cancer |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5745650/ https://ncbi.nlm.nih.gov/pubmed/29282095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0749-x |
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