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On the Structure and Mechanism of Two-Pore Channels

In eukaryotes, two-pore channels (TPC1-3) comprise a family of ion channels that regulate the conductance of Na(+) and Ca(2+) ions across cellular membranes. TPC1-3 form endolysosomal channels, but TPC3 can also function in the plasma membrane. TPC1/3 are voltage-gated channels, but TPC2 opens in re...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:FEBS J
Päätekijät: Kintzer, Alexander F., Stroud, Robert M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745306/
https://ncbi.nlm.nih.gov/pubmed/28656706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14154
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