Coordination of platelet agonist signaling during the hemostatic response in vivo

The local microenvironment within an evolving hemostatic plug shapes the distribution of soluble platelet agonists, resulting in a gradient of platelet activation. We previously showed that thrombin activity at a site of vascular injury is spatially restricted, resulting in robust activation of a su...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Shen, Jian, Sampietro, Sara, Wu, Jie, Tang, Juan, Gupta, Shuchi, Matzko, Chelsea N., Tang, Chaojun, Yu, Ying, Brass, Lawrence F., Zhu, Li, Stalker, Timothy J.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2017
Subjects:
Thrombosis and Hemostasis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745130/
https://ncbi.nlm.nih.gov/pubmed/29296928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009498
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