A systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets

Hemostatic thrombi develop a characteristic architecture in which a core of highly activated platelets is covered by a shell of less-activated platelets. Here we have used a systems biology approach to examine the interrelationship of this architecture with transport rates and agonist distribution i...

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Главные авторы: Welsh, John D., Stalker, Timothy J., Voronov, Roman, Muthard, Ryan W., Tomaiuolo, Maurizio, Diamond, Scott L., Brass, Lawrence F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
Предметы:
Thrombosis and Hemostasis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162110/
https://ncbi.nlm.nih.gov/pubmed/24951424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-550335
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