Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet

BACKGROUND: Human eNOS (NOS3) polymorphisms that lower its expression are associated with advanced diabetic nephropathy (DN), and the lack of eNOS accelerates DN in diabetic mice. Diabetes is associated with fibrin deposition. Lack of nitric oxide and fatty acids stimulate the NF-kB pathway, which i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Thromb Haemost
Egile Nagusiak: Li, Feng, Wang, Chih-Hong, Wang, Jian-Guo, Thai, Tiffany, Boysen, Gunnar, Xu, Longquan, Turner, Adam L, Wolberg, Alisa S., Mackman, Nigel, Maeda, Nobuyo, Takahashi, Nobuyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744483/
https://ncbi.nlm.nih.gov/pubmed/20626618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.03976.x
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