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Promoter mutagenesis for fine‐tuning expression of essential genes in Mycobacterium tuberculosis

A range of regulated gene expression systems has been developed for mycobacteria in the last few years to facilitate the study of essential genes, validate novel drug targets and evaluate their vulnerability. Among these, the TetR/Pip‐OFF repressible promoter system was successfully used in several...

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Detalhes bibliográficos
Publicado no:Microb Biotechnol
Main Authors: Boldrin, Francesca, Degiacomi, Giulia, Serafini, Agnese, Kolly, Gaëlle S., Ventura, Marcello, Sala, Claudia, Provvedi, Roberta, Palù, Giorgio, Cole, Stewart T., Manganelli, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743821/
https://ncbi.nlm.nih.gov/pubmed/29076636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.12875
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