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Characterization of a Mycobacterium tuberculosis ESX-3 Conditional Mutant: Essentiality and Rescue by Iron and Zinc

Recently, a novel type of secretory pathway, type VII secretion systems (T7SSs), has been characterized in mycobacteria. The chromosomes of Mycobacterium tuberculosis and Mycobacterium bovis encode five T7SSs (ESX-1 to ESX-5). The best characterized of them, ESX-1, is involved in host-pathogen inter...

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Bibliografiske detaljer
Main Authors: Serafini, Agnese, Boldrin, Francesca, Palù, Giorgio, Manganelli, Riccardo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753049/
https://ncbi.nlm.nih.gov/pubmed/19684129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00756-09
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