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Xer Site-Specific Recombination, an Efficient Tool To Introduce Unmarked Deletions into Mycobacteria

Genetic manipulation of mycobacteria still represents a serious challenge due to the lack of tools and selection markers. In this report, we describe the development of an intrinsically unstable excisable cassette for introduction of unmarked mutations in both Mycobacterium smegmatis and Mycobacteri...

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Detalhes bibliográficos
Main Authors: Cascioferro, Alessandro, Boldrin, Francesca, Serafini, Agnese, Provvedi, Roberta, Palù, Giorgio, Manganelli, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916470/
https://ncbi.nlm.nih.gov/pubmed/20543044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00382-10
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