Structural Characterization of Ferrous Ion Binding to Retinal Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors

Sensory guanylate cyclases (zGCs) in zebrafish photoreceptors are regulated by a family of guanylate cyclase activator proteins (called GCAP1-7). GCAP5 contains two non-conserved cysteine residues (Cys15 and Cys17) that could in principle bind to biologically active transition state metal ions (Zn(2...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Lim, Sunghyuk, Scholten, Alexander, Manchala, Grace, Cudia, Diana, Zlomke-Sell, Sarah-Karina, Koch, Karl-W., Ames, James B.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743585/
https://ncbi.nlm.nih.gov/pubmed/29172459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01029
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