A cell-penetrating whole molecule antibody targeting intracellular HBx suppresses hepatitis B virus via TRIM21-dependent pathway

Rationale: Monoclonal antibodies (mAbs) mostly targeting extracellular or cell surface molecules have been widely used in the treatment of various diseases. However, mAbs cannot pass through the cell membrane as efficiently as small compounds, thus limiting their use against intracellular targets. M...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhang, Jun-Fang, Xiong, Hua-Long, Cao, Jia-Li, Wang, Shao-Juan, Guo, Xue-Ran, Lin, Bi-Yun, Zhang, Ying, Zhao, Jing-Hua, Wang, Ying-Bin, Zhang, Tian-Ying, Yuan, Quan, Zhang, Jun, Xia, Ning-Shao
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743566/
https://ncbi.nlm.nih.gov/pubmed/29290826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.20047
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados