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Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway

Quercetin is proven to have anticancer effects for many cancers. However, the role of tumor suppressor p53 on quercetin’s radiosensitization and regulation of endoplasmic reticulum (ER) stress response in this process remains obscure. Here, quercetin exposure resulted in ER stress, prolonged DNA rep...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Gong, Cheng, Yang, Zongyuan, Zhang, Lingyun, Wang, Yuehua, Gong, Wei, Liu, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743179/
https://ncbi.nlm.nih.gov/pubmed/29317830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S147316
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