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Activating Akt1 mutations alter DNA double strand break repair and radiosensitivity
The survival kinase Akt has clinical relevance to radioresistance. However, its contributions to the DNA damage response, DNA double strand break (DSB) repair and apoptosis remain poorly defined and often contradictory. We used a genetic approach to explore the consequences of genetic alterations of...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314324/ https://ncbi.nlm.nih.gov/pubmed/28209968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42700 |
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