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Reconciling contradictory findings: Glucose transporter 1 (GLUT1) functions as an oligomer of allosteric, alternating access transporters

Recent structural studies suggest that GLUT1 (glucose transporter 1)-mediated sugar transport is mediated by an alternating access transporter that successively presents exofacial (e2) and endofacial (e1) substrate-binding sites. Transport studies, however, indicate multiple, interacting (allosteric...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lloyd, Kenneth P., Ojelabi, Ogooluwa A., De Zutter, Julie K., Carruthers, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743077/
https://ncbi.nlm.nih.gov/pubmed/29066623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815589
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