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A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1
Spindlin1 (SPIN1) is a transcriptional coactivator with critical functions in embryonic development and emerging roles in cancer. SPIN1 harbors three Tudor domains, two of which engage the tail of histone H3 by reading the H3–Lys-4 trimethylation and H3–Arg-8 asymmetric dimethylation marks. To gain...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5743059/ https://ncbi.nlm.nih.gov/pubmed/29061846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.814913 |
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