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A gain-of-function mouse model identifies PRMT6 as a NF-κB coactivator
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that modifies histone tails. To help elucidate the biological function of PRMT6 in vivo, we generated transgenic mice that ubiquitously express PRMT6 fused to the hormone-binding portion of the estrogen receptor (ER*). The ER*-PRMT6 fu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117762/ https://ncbi.nlm.nih.gov/pubmed/24939901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku530 |
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