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Telomere Shortening in Hematological Malignancies with Tetraploidization—A Mechanism for Chromosomal Instability?

Aneuploidy, the presence of an abnormal number of chromosomes in a cell, is one of the most obvious differences between normal and cancer cells. There is, however, debate on how aneuploid cells arise and whether or not they are a cause or a consequence of tumorigenesis. Further, it is important to d...

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Publicat a:Cancers (Basel)
Autor principal: Kjeldsen, Eigil
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742813/
https://ncbi.nlm.nih.gov/pubmed/29189717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers9120165
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