Disulfiram combined with copper inhibits metastasis and epithelial–mesenchymal transition in hepatocellular carcinoma through the NF‐κB and TGF‐β pathways

Late‐stage hepatocellular carcinoma (HCC) usually has a low survival rate because of the high risk of metastases and the lack of an effective cure. Disulfiram (DSF) has copper (Cu)‐dependent anticancer properties in vitro and in vivo. The present work aims to explore the anti‐metastasis effects and...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Li, Yi, Wang, Li‐Hui, Zhang, Hao‐Tian, Wang, Ya‐Ting, Liu, Shuai, Zhou, Wen‐Long, Yuan, Xiang‐Zhong, Li, Tian‐Yang, Wu, Chun‐Fu, Yang, Jing‐Yu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742719/
https://ncbi.nlm.nih.gov/pubmed/29148232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13334
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