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The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein

This review summarizes the mechanisms of the initiator protein DnaA in replication initiation and its regulation in Escherichia coli. The chromosomal origin (oriC) DNA is unwound by the replication initiation complex to allow loading of DnaB helicases and replisome formation. The initiation complex...

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Katayama, Tsutomu, Kasho, Kazutoshi, Kawakami, Hironori
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742627/
https://ncbi.nlm.nih.gov/pubmed/29312202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02496
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