The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein

This review summarizes the mechanisms of the initiator protein DnaA in replication initiation and its regulation in Escherichia coli. The chromosomal origin (oriC) DNA is unwound by the replication initiation complex to allow loading of DnaB helicases and replisome formation. The initiation complex...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Katayama, Tsutomu, Kasho, Kazutoshi, Kawakami, Hironori
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742627/
https://ncbi.nlm.nih.gov/pubmed/29312202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02496
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