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Implication of mutagenesis and precursor supplementation towards the enhancement of lipstatin (an antiobesity agent) biosynthesis through submerged fermentation using Streptomyces toxytricini

In the present study, lipstatin production was studied from different mutants of Streptomyces toxytricini which were developed using ultraviolet radiation (exposure time 30 s, 1, 2, 5 and 10 min), ethyl methane sulfonte, methyl methane sulfonate (MMS) and N-methyl-N′-intro-N-nitrosoguanidine (NTG) t...

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Bibliographic Details
Published in:3 Biotech
Main Authors: Kumar, Punit, Dubey, Kashyap Kumar
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742565/
https://ncbi.nlm.nih.gov/pubmed/29291142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-017-1049-2
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