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The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini

Streptomyces toxytricini produces lipstatin, a specific inhibitor of pancreatic lipase, which is derived from two fatty acid moieties with eight and 14 carbon atoms. The pccB gene locus in 10.6 kb fragment of S. toxytricini chromosomal DNA contains three genes for acyl-coenzyme A carboxylase (ACCase...

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Autori principali: Demirev, Atanas V., Khanal, Anamika, Sedai, Bhishma R., Lim, Si Kyu, Na, Min Kyun, Nam, Doo Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886142/
https://ncbi.nlm.nih.gov/pubmed/20437235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-010-2587-2
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