Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model

Mycobacterium tuberculosis is the pathogenic bacterium that causes tuberculosis (TB), one of the most lethal infectious diseases in the world. The only vaccine against TB is minimally protective, and multi-drug resistant TB necessitates new therapeutics to treat infection. Developing new therapies r...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Warsinske, Hayley C., Pienaar, Elsje, Linderman, Jennifer J., Mattila, Joshua T., Kirschner, Denise E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742530/
https://ncbi.nlm.nih.gov/pubmed/29326718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01843
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