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Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas.

Drug resistant tuberculosis is increasing world-wide. Resistance against isoniazid (INH), rifampicin (RIF), or both (multi-drug resistant TB, MDR-TB) is of particular concern, since INH and RIF form part of the standard regimen for TB disease. While it is known that suboptimal treatment can lead to...

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Bibliografiska uppgifter
Huvudupphovsmän: Elsje Pienaar, Jennifer J Linderman, Denise E Kirschner
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2018-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC5944939?pdf=render
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