Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice

Neuronal degeneration following traumatic brain injury (TBI) leads to intracellular accumulation of dysfunctional proteins and organelles. Autophagy may serve to facilitate degradation to overcome protein debris load and therefore be an important pro-survival factor. On the contrary, clearing may se...

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Vydáno v:Front Neurosci
Hlavní autoři: Sebastiani, Anne, Gölz, Christina, Sebastiani, Philipp G., Bobkiewicz, Wiesia, Behl, Christian, Mittmann, Thomas, Thal, Serge C., Engelhard, Kristin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742218/
https://ncbi.nlm.nih.gov/pubmed/29311767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00678
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