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PAI-1 but Not PAI-2 Gene Deficiency Attenuates Ischemic Brain Injury After Experimental Stroke

After stroke, secondary brain damage is influenced by the extent of fibrin clot formation. This is counteracted by the endogenous fibrinolysis. Of major interest are the key players of the fibrinolytic plasminogen activator system including the urokinase plasminogen activator (uPA), the tissue-type...

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Detalhes bibliográficos
Publicado no:Transl Stroke Res
Main Authors: Griemert, Eva-Verena, Recarte Pelz, Kirsten, Engelhard, Kristin, Schäfer, Michael K., Thal, Serge C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647425/
https://ncbi.nlm.nih.gov/pubmed/29978354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-018-0644-9
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