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Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice

Neuronal degeneration following traumatic brain injury (TBI) leads to intracellular accumulation of dysfunctional proteins and organelles. Autophagy may serve to facilitate degradation to overcome protein debris load and therefore be an important pro-survival factor. On the contrary, clearing may se...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Sebastiani, Anne, Gölz, Christina, Sebastiani, Philipp G., Bobkiewicz, Wiesia, Behl, Christian, Mittmann, Thomas, Thal, Serge C., Engelhard, Kristin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742218/
https://ncbi.nlm.nih.gov/pubmed/29311767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00678
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