Donepezil suppresses intracellular Ca(2+) mobilization through the PI3K pathway in rodent microglia

BACKGROUND: Microglia are resident innate immune cells which release many factors including proinflammatory cytokines or nitric oxide (NO) when they are activated in response to immunological stimuli. Pathophysiology of Alzheimer’s disease (AD) is related to the inflammatory responses mediated by mi...

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Библиографические подробности
Опубликовано в: :J Neuroinflammation
Главные авторы: Haraguchi, Yoshinori, Mizoguchi, Yoshito, Ohgidani, Masahiro, Imamura, Yoshiomi, Murakawa-Hirachi, Toru, Nabeta, Hiromi, Tateishi, Hiroshi, Kato, Takahiro A., Monji, Akira
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741946/
https://ncbi.nlm.nih.gov/pubmed/29273047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1033-0
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