Donepezil suppresses intracellular Ca(2+) mobilization through the PI3K pathway in rodent microglia

BACKGROUND: Microglia are resident innate immune cells which release many factors including proinflammatory cytokines or nitric oxide (NO) when they are activated in response to immunological stimuli. Pathophysiology of Alzheimer’s disease (AD) is related to the inflammatory responses mediated by mi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neuroinflammation
Egile Nagusiak: Haraguchi, Yoshinori, Mizoguchi, Yoshito, Ohgidani, Masahiro, Imamura, Yoshiomi, Murakawa-Hirachi, Toru, Nabeta, Hiromi, Tateishi, Hiroshi, Kato, Takahiro A., Monji, Akira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741946/
https://ncbi.nlm.nih.gov/pubmed/29273047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1033-0
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