Brain-derived Neurotrophic Factor (BDNF) Induces Sustained Intracellular Ca(2+) Elevation through the Up-regulation of Surface Transient Receptor Potential 3 (TRPC3) Channels in Rodent Microglia

Microglia are immune cells that release factors, including proinflammatory cytokines, nitric oxide (NO), and neurotrophins, following activation after disturbance in the brain. Elevation of intracellular Ca(2+) concentration ([Ca(2+)](i)) is important for microglial functions such as the release of...

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Detalhes bibliográficos
Main Authors: Mizoguchi, Yoshito, Kato, Takahiro A., Seki, Yoshihiro, Ohgidani, Masahiro, Sagata, Noriaki, Horikawa, Hideki, Yamauchi, Yusuke, Sato-Kasai, Mina, Hayakawa, Kohei, Inoue, Ryuji, Kanba, Shigenobu, Monji, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140290/
https://ncbi.nlm.nih.gov/pubmed/24811179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555334
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