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Coffee extract and caffeine enhance the heat shock response and promote proteostasis in an HSF-1-dependent manner in Caenorhabditis elegans

As the population ages, there is a critical need to uncover strategies to combat diseases of aging. Studies in the soil-dwelling nematode Caenorhabditis elegans have demonstrated the protective effects of coffee extract and caffeine in promoting the induction of conserved longevity pathways includin...

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Publicado en:Cell Stress Chaperones
Main Authors: Brunquell, Jessica, Morris, Stephanie, Snyder, Alana, Westerheide, Sandy D.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741582/
https://ncbi.nlm.nih.gov/pubmed/28674941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0824-7
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