The small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two neurodegenerative diseases in which similar pathogenic mechanisms are involved. Both diseases associate to the high propensity of specific misfolded proteins, like TDP-43 or FUS, to mislocalize and aggregate. This is partl...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Cristofani, Riccardo, Crippa, Valeria, Vezzoli, Giulia, Rusmini, Paola, Galbiati, Mariarita, Cicardi, Maria Elena, Meroni, Marco, Ferrari, Veronica, Tedesco, Barbara, Piccolella, Margherita, Messi, Elio, Carra, Serena, Poletti, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741577/
https://ncbi.nlm.nih.gov/pubmed/28608264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0806-9
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