Quantification of huntingtin protein species in Huntington’s disease patient leukocytes using optimised electrochemiluminescence immunoassays

BACKGROUND: Huntington’s disease (HD) is an autosomal dominant neurodegenerative condition caused by an expanded CAG repeat in the gene encoding huntingtin (HTT). Optimizing peripheral quantification of huntingtin throughout the course of HD is valuable not only to illuminate the natural history and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hensman Moss, Davina J., Robertson, Nicola, Farmer, Ruth, Scahill, Rachael I., Haider, Salman, Tessari, Michela A., Flynn, Geraldine, Fischer, David F., Wild, Edward J., Macdonald, Douglas, Tabrizi, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741241/
https://ncbi.nlm.nih.gov/pubmed/29272284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189891
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