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Mesenchymal Stem Cell Differentiation into Adipocytes Is Equally Induced by Insulin and Proinsulin In Vitro

BACKGROUND AND OBJECTIVES: In advanced β-cell dysfunction, proinsulin is increasingly replacing insulin as major component of the secretion product. It has been speculated that proinsulin has at least the same adipogenic potency than insulin, leading to an increased tendency of lipid tissue formatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Stem Cells
Hauptverfasser: Pfützner, Andreas, Schipper, Dorothee, Pansky, Andreas, Kleinfeld, Claudia, Roitzheim, Barbara, Tobiasch, Edda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Stem Cell Research 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741196/
https://ncbi.nlm.nih.gov/pubmed/29186653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc17033
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