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Mesenchymal Stem Cell Differentiation into Adipocytes Is Equally Induced by Insulin and Proinsulin In Vitro

BACKGROUND AND OBJECTIVES: In advanced β-cell dysfunction, proinsulin is increasingly replacing insulin as major component of the secretion product. It has been speculated that proinsulin has at least the same adipogenic potency than insulin, leading to an increased tendency of lipid tissue formatio...

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Detalhes bibliográficos
Publicado no:Int J Stem Cells
Main Authors: Pfützner, Andreas, Schipper, Dorothee, Pansky, Andreas, Kleinfeld, Claudia, Roitzheim, Barbara, Tobiasch, Edda
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Stem Cell Research 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741196/
https://ncbi.nlm.nih.gov/pubmed/29186653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc17033
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