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Mesenchymal Stem Cell Differentiation into Adipocytes Is Equally Induced by Insulin and Proinsulin In Vitro

BACKGROUND AND OBJECTIVES: In advanced β-cell dysfunction, proinsulin is increasingly replacing insulin as major component of the secretion product. It has been speculated that proinsulin has at least the same adipogenic potency than insulin, leading to an increased tendency of lipid tissue formatio...

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Bibliografiset tiedot
Julkaisussa:Int J Stem Cells
Päätekijät: Pfützner, Andreas, Schipper, Dorothee, Pansky, Andreas, Kleinfeld, Claudia, Roitzheim, Barbara, Tobiasch, Edda
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Korean Society for Stem Cell Research 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741196/
https://ncbi.nlm.nih.gov/pubmed/29186653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc17033
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