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Mesenchymal Stem Cell Differentiation into Adipocytes Is Equally Induced by Insulin and Proinsulin In Vitro

BACKGROUND AND OBJECTIVES: In advanced β-cell dysfunction, proinsulin is increasingly replacing insulin as major component of the secretion product. It has been speculated that proinsulin has at least the same adipogenic potency than insulin, leading to an increased tendency of lipid tissue formatio...

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Publicado en:Int J Stem Cells
Autores principales: Pfützner, Andreas, Schipper, Dorothee, Pansky, Andreas, Kleinfeld, Claudia, Roitzheim, Barbara, Tobiasch, Edda
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Stem Cell Research 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741196/
https://ncbi.nlm.nih.gov/pubmed/29186653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc17033
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