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TFIIH generates a six base-pair open complex during RNAP II transcription initiation and start-site scanning
Eukaryotic mRNA transcription initiation is directed by the formation of the megaDalton-sized pre-initiation complex (PIC). After PIC formation, double-stranded DNA is unwound to form a single-stranded DNA bubble and the template strand is loaded into the polymerase active site. DNA opening is catal...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741190/ https://ncbi.nlm.nih.gov/pubmed/29106413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3500 |
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