The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning.

The general transcription factor TFIIH contains three ATP-dependent catalytic activities. TFIIH functions in nucleotide excision repair primarily as a DNA helicase and in Pol II transcription initiation as a dsDNA translocase and protein kinase. During initiation, the XPB/Ssl2 subunit of TFIIH coupl...

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Pubblicato in:J Mol Biol
Autori principali: Tomko, Eric J., Luyties, Olivia, Rimel, Jenna K., Tsai, Chi-Lin, Fuss, Jill O., Fishburn, James, Hahn, Steven, Tsutakawa, Susan E., Taatjes, Dylan J., Galburt, Eric A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327364/
https://ncbi.nlm.nih.gov/pubmed/33453189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166813
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