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Uncoupling promoter opening from start site scanning
Whereas RNA polymerase II (pol II) transcription start sites (TSSs) occur about 30–35 bp downstream of the TATA box in metazoans, TSSs are located 40–120 bp downstream in S. cerevisiae. Promoter melting begins about 12 bp downstream in all eukaryotes, so pol II is presumed to “scan” further downstre...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4490988/ https://ncbi.nlm.nih.gov/pubmed/26073544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.05.021 |
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