ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, and several molecular pathways that underlie the molecular tumorigenesis of HNSCC have been identified. Among them, amplification or overexpression of ΔNp63 isoforms is observed in the majority of HNSCCs. Here,...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Compagnone, Mirco, Gatti, Veronica, Presutti, Dario, Ruberti, Giovina, Fierro, Claudia, Markert, Elke Katrin, Vousden, Karen H., Zhou, Huiqing, Mauriello, Alessandro, Anemone, Lucia, Bongiorno-Borbone, Lucilla, Melino, Gerry, Peschiaroli, Angelo
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740608/
https://ncbi.nlm.nih.gov/pubmed/29162693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711777114
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