ΔNp63-mediated regulation of hyaluronic acid metabolism and signaling supports HNSCC tumorigenesis

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, and several molecular pathways that underlie the molecular tumorigenesis of HNSCC have been identified. Among them, amplification or overexpression of ΔNp63 isoforms is observed in the majority of HNSCCs. Here,...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Compagnone, Mirco, Gatti, Veronica, Presutti, Dario, Ruberti, Giovina, Fierro, Claudia, Markert, Elke Katrin, Vousden, Karen H., Zhou, Huiqing, Mauriello, Alessandro, Anemone, Lucia, Bongiorno-Borbone, Lucilla, Melino, Gerry, Peschiaroli, Angelo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740608/
https://ncbi.nlm.nih.gov/pubmed/29162693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711777114
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