Activity of Meropenem-Vaborbactam in Mouse Models of Infection Due to KPC-Producing Carbapenem-Resistant Enterobacteriaceae

Meropenem-vaborbactam (Vabomere) is highly active against Gram-negative pathogens, especially Klebsiella pneumoniae carbapenemase (KPC)-producing, carbapenem-resistant Enterobacteriaceae. The objective of these studies was to evaluate the efficacy of meropenem alone and in combination with vaborbact...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Sabet, Mojgan, Tarazi, Ziad, Nolan, Thomas, Parkinson, Jonathan, Rubio-Aparicio, Debora, Lomovskaya, Olga, Dudley, Michael N., Griffith, David C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740387/
https://ncbi.nlm.nih.gov/pubmed/29109160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01446-17
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