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Activity of Simulated Human Dosage Regimens of Meropenem and Vaborbactam against Carbapenem-Resistant Enterobacteriaceae in an In Vitro Hollow-Fiber Model

The objective of these studies was to evaluate the exposures of meropenem and vaborbactam that would produce antibacterial activity and prevent resistance development in carbapenem-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains when tested at an inoculum of...

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發表在:Antimicrob Agents Chemother
Main Authors: Sabet, Mojgan, Tarazi, Ziad, Rubio-Aparicio, Debora, Nolan, Thomas G., Parkinson, Jonathan, Lomovskaya, Olga, Dudley, Michael N., Griffith, David C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786802/
https://ncbi.nlm.nih.gov/pubmed/29133570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01969-17
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